Description
🧬 Overview
SS-31 is a synthetic peptide designed to selectively target mitochondria, the energy-producing structures within cells. Unlike many compounds, it directly interacts with mitochondrial membranes, making it a key focus in research related to energy metabolism, aging, and cellular protection.
Its ability to improve mitochondrial efficiency has positioned it as an important compound in advanced metabolic and longevity studies.
⚙️ Technical Profile
- Peptide Name: SS-31 (Elamipretide)
- Type: Mitochondria-targeted peptide
- Sequence: D-Arg-Dmt-Lys-Phe-NH₂
- Molecular Formula: C₃₂H₄₉N₉O₅
- Molecular Weight: ~639.8 g/mol
- Structure: Tetrapeptide analog
- Target: Inner mitochondrial membrane (cardiolipin interaction)
- Biological Role: Mitochondrial protection and energy support
- Purity (Research Grade): Typically ≥98%
- Form: Lyophilized powder
- Solubility: Water-soluble
⚡ Mechanism of Action
SS-31 works by selectively binding to cardiolipin, a phospholipid found in the inner mitochondrial membrane. This interaction helps stabilize mitochondrial structure and improve the efficiency of the electron transport chain.
By enhancing mitochondrial function, SS-31 supports increased ATP production and reduces the generation of reactive oxygen species (ROS). This leads to improved cellular energy output and reduced oxidative stress.
It also helps protect cells from mitochondrial dysfunction, which is a key factor in aging and metabolic decline.
🔬 Research Context
SS-31 has been extensively studied in research related to mitochondrial dysfunction, aging, and metabolic disorders. It is commonly explored in models involving muscle fatigue, cardiovascular health, and neurodegenerative conditions.
Research highlights its potential to improve energy efficiency at the cellular level and protect against oxidative damage. It is also being investigated for its role in enhancing endurance and recovery in performance-related studies.
Ongoing studies continue to evaluate its broader applications in mitochondrial health and longevity science.


Reviews
There are no reviews yet.