Description

🧬 Overview

KPV (Lys-Pro-Val) is a naturally derived tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). Despite its small size, it has shown strong potential in research related to inflammation control and immune system regulation. Its targeted action makes it a key compound in studies involving skin health, gut function, and inflammatory conditions.

⚙️ Technical Profile

• Peptide Name: KPV (Lys-Pro-Val)
• Type: Anti-inflammatory tripeptide
• Sequence Length: 3 amino acids
• Molecular Formula: C₁₆H₂₈N₄O₄
• Molecular Weight: ~340.4 g/mol
• Structure: Linear tripeptide
• Origin: Derived from α-MSH
• Biological Role: Inflammation modulation and immune support
• Purity (Research Grade): Typically ≥98%
• Form: Lyophilized powder / topical or oral research formats
• Solubility: Water-soluble

⚡ Mechanism of Action

KPV works by modulating inflammatory pathways, particularly through inhibition of pro-inflammatory cytokines such as TNF-α and IL-6. This helps reduce excessive inflammatory responses in research models.

It also interacts with melanocortin receptors, contributing to immune regulation and cellular balance. Due to its small size, KPV is easily absorbed and can act locally in targeted tissues such as the skin and gastrointestinal tract.

Through these mechanisms, it supports reduced inflammation and improved tissue stability.

🔬 Research Context

KPV has been widely studied in research related to inflammatory conditions, including skin disorders and gastrointestinal inflammation. It is commonly explored for its potential to reduce irritation, promote healing, and support immune balance.

Research also investigates its applications in dermatology, including acne, eczema, and wound healing models. Its ability to provide anti-inflammatory effects without broad systemic impact makes it a unique compound in targeted peptide research.

Ongoing studies continue to evaluate its broader applications in immune health, gut support, and skin regeneration.